Dupuytren’s disease, also known as Dupuytren’s contracture or palmar fibromatosis, causes a hand and finger deformity where the finger(s) gradually bend and contract toward the palm. People are made aware that they may have Dupuytren’s disease when they notice that their finger won’t straighten and that there is a tight, cordlike structure in their palm. Dupuytren’s disease can range in severity from the early, mildest cases consisting of a single nodule in the palm that may never progress, to the more severe cases of multiple finger involvement.